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Search Results for " protein i "

Targets

Compounds

Natural Products

438

Recombinant Proteins

Reagents

Cat No.	Product Name	Synonyms	Targets
T2444	KNK437	Heat Shock Protein Inhibitor I	HSP
	KNK437 (Heat Shock Protein Inhibitor I), a pan-HSP inhibitor, suppresses the synthesis of inducible HSPs(HSP105, HSP72, and HSP40).		HSP
T6859	I-BRD9	GSK602	Epigenetic Reader Domain
	I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3.		Epigenetic Reader Domain
T8476	RSVA405	RSVA 405	AMPK , STAT , Autophagy
	RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitor		AMPK , STAT , Autophagy
T6513	Bisindolylmaleimide I	GF109203X,Go 6850	PDGFR , PKC
	Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.		PDGFR , PKC
T0708	Oxaprozin	Oxaprozinum,Wy21743	NF-κB , COX
	Oxaprozin (Oxaprozinum) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of oxaprozin is as a Cyclooxygenase Inhibitor. The chemical classification of oxaprozin is Nonsteroidal Anti-inflammatory Compound...		NF-κB , COX
T3969	I-CBP112		Epigenetic Reader Domain , Histone Acetyltransferase
	I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains.		Epigenetic Reader Domain , Histone Acetyltransferase
T67748	ROCK-IN-5		ROCK , ERK
	ROCK-IN-5 (compound I-B-37) is a potent inhibitor of protein kinases, including ROCK, ERK, GSK, and AGC. ROCK-IN-5 exhibits the potential for cardiac, proliferative and neurodegenerative diseases research.		ROCK , ERK
T72026	P53-MDM2-IN-1		Mdm2 , p53
	p53-MDM2-IN-1 (Example 30), an inhibitor targeting the p53-MDM2/X protein interaction, exhibits a K i value of 23.35 µM. This compound holds potential for applications in anti-tumor research.		Mdm2 , p53
T6549	Isepamicin sulfate	Isepamicine (Isepamycin,Isepamicin Sulphate,Isepacin,sch21420) Sulphate	Antibacterial , Antibiotic
	Isepamicin sulfate (sch21420) Sulphate) , an aminoglycoside antibacterial with good activity against strains producing type I 6-acetyltransferase, inhibits bacterial protein synthesis by targeting the bacterial 30S ribos...		Antibacterial , Antibiotic
T5114	Pyridaben		Calcium Channel , Parasite
	Pyridaben is a METI acaricide that inhibits mitochondrial electron transport at complex I (METI; Ki = 0.36 nmol/mg protein in rat brain mitochondria).		Calcium Channel , Parasite
TP1777L	P2Ca acetate(142606-55-1 free base)		Others
	p2Ca acetate is a naturally processed peptide that derives from a ubiquitous enzyme, alpha-ketoglutarate dehydrogenase, and is recognized in association with the class I MHC protein, Ld, by a CTL clone (2C).		Others
T15507	Hycanthone	Etrenol(mesylate),Win 249-33	DNA/RNA Synthesis , Topoisomerase , Parasite
	Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal. Hycanthone is a DNA intercalator that inhibits RNA synthesis and DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibit...		DNA/RNA Synthesis , Topoisomerase , Parasite
T14998	Copanlisib dihydrochloride	BAY 80-6946 dihydrochloride	Apoptosis , PI3K , mTOR
	Copanlisib dihydrochloride (BAY 80-6946 dihydrochloride) is an ATP-competitive pan-class I PI3K inhibitor (IC50s: 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kα, PI3Kδ, PI3Kβ and PI3Kγ). Copanlisib dihydrochloride has super...		Apoptosis , PI3K , mTOR
T77584	Tubulin inhibitor 35	Tubulin IN 35	Apoptosis , Microtubule Associated , Topoisomerase
	Tubulin inhibitor 35 (Tubulin IN 35) is a potent dual inhibitor of topoisomerase I and microtubule protein polymerization with antitumor activity, inhibits migration and invasion of MGC-803 and RKO cell lines, interrupts...		Apoptosis , Microtubule Associated , Topoisomerase
T6336	Amonafide	NSC308847,AS1413,Nafidimide,AS1413,Quinamed	Topoisomerase
	Amonafide (NSC-308847,AS1413)(AS1413) produces protein-associated DNA-strand breaks through a topoisomerase II-mediated reaction, but does not produce topoisomerase I-mediated DNA cleavage.		Topoisomerase
T11500L	GSK3368715 dihydrochloride	EPZ019997 dihydrochloride,GSK3368715 2HCl,EPZ019997 2HCl	Histone Methyltransferase
	GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is an orally active and potent inhibitor of type I protein arginine methyltransferases (PRMTs) with anticancer and antitumor activity, inhibiting PRMT1, PRMT3, PRMT4...		Histone Methyltransferase
T9642	ZW4864 free base		Wnt/beta-catenin
	ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction ( β catenin/BCL9 PPI ) inhibitor. ZW4864 (free base) inhibits β catenin/BCL9 PPI with a K i value of 0.76 μM an...		Wnt/beta-catenin
T61338	MS023 dihydrochloride	MS023 2HCl	Histone Methyltransferase
	MS023 dihydrochloride (MS023 2HCl) is a selective, cytosolic and highly potent inhibitor of human type I protein arginine methyltransferases (PRMTs) with antitumour activity, inhibits PRMT1, PRMT3, PRMT4, PRMT6, and PRMT...		Histone Methyltransferase
T60196	IHMT-PI3Kδ-372 S-isomer		PI3K
	IHMT-PI3Kδ-372 S-isomer is a potent and selective PI3Kδ inhibitor with an IC50 of 14 nM. IHMT-PI3Kδ-372 S-isomer shows high selectivity over other class I PI3Ks (56∼83 fold) and other protein kinases. IHMT-PI3Kδ-372 can ...		PI3K
T7084	2-Bromo-4'-hydroxyacetophenone	SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide	Phosphatase
	2-Bromo-4'-hydroxyacetophenone(PTP Inhibitor I) is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor that covalently blocks the catalytic domain of the Src homology region 2 domain-containing phosphatase (SH...		Phosphatase
T2055	WS3		EGFR , IκB/IKK
	WS3, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.		EGFR , IκB/IKK
T72322	R 59-022 hydrochloride	DKGI-I hydrochloride,Diacylglycerol kinase inhibitor I hydrochloride,DKGI-I hydrochloride ; Diacylglycerol kinase inhibitor I hydrochloride	5-HT Receptor , PKC
	R 59-022 hydrochloride (DKGI-I hydrochloride) is a 5-HT Receptor antagonist that activates protein kinase C (PKC).R 59-022 hydrochloride is a DGK inhibitor (IC50:2.8 µM) that inhibits the phosphorylation of OAG to OAPA.R...		5-HT Receptor , PKC
T16703	Quarfloxin	CX-3543	DNA/RNA Synthesis
	Quarfloxin (CX-3543) is a fluoroquinolone derivative with antineoplastic activity with IC50 values in the nanomolar range in neuroblastoma cells. Quarfloxin disrupts the interaction between the nucleolin protein and a G-...		DNA/RNA Synthesis
T38050	CP-609754		Transferase
	CP-609754 (LNK-754) is a potent and reversible farnesyltransferase inhibitor with potential anticancer activity.The IC50 for inhibiting farnesylation of recombinant human H-Ras is 0.57 ng/mL and recombinant K-Ras is 46 n...		Transferase
T71135	Calphostin I
	Calphostin I is isolated from the fungus Cladosporium cladosporioides and is an inhibitor of protein kinase C (PKC).
T17234	VI 16832		Others
	VI 16832 is a broad spectrum Type I kinase inhibitor. It also used for the comparative expression analysis of protein kinases in different cancer cell lines.		Others
T24901	Troponin I (104-115)	Ac-Gly-lys-phe-lys-arg-pro-pro-leu-arg-arg-val-arg-NH2,Tni peptide (104-115)
	Troponin I is a cardiac and skeletal muscle protein useful in the laboratory diagnosis of a heart attack. Troponin I is a part of the troponin protein complex, where it binds to actin in thin myofilaments to hold the ac...
T39679	Lenalidomide-I
	Lenalidomide-I (Compound 72) is a derivative of the cereblon (CRBN) ligand, Lenalidomide, with affinity for E3 ubiquitin ligase. It facilitates the recruitment of CRBN protein. Lenalidomide-I can be utilized in PROTACs, ...
T23629	Adam I-123	Adam I 123,Adam I123
	Adam I-123 is a radiopharmaceutical containing the serotonin transporter (SERT) ligand, with SERT-binding and radioisotope activities. SERT is a monoamine transporter protein found in the membranes of neurons and platele...
T39870	5-HT7R antagonist 1 free base	5-HT7R antagonist 1 free base
	5-HT7R antagonist 1 (free base) is a G protein-biased antagonist for the 5-HT 7 R receptor, with a dissociation constant (K i) of 6.5 nM.
T25346	DMH2	DMH-2,DMH 2
	DMH2 is an antagonist of bone morphogenetic protein (BMP) type I receptor. It acts by decreasing growth and inducing cell death of lung cancer cell lines.
T22342	GSK3368715 3HCl	EPZ019997 3HCl,GSK3368715(EPZ019997)	Histone Methyltransferase
	GSK3368715, a potent inhibitor of type I protein arginine methyltransferases (PRMT), could inhibit PRMT1, 3, 4, 6 and 8 with Kiapp vaules ranging from 1.5 to 81 nM.		Histone Methyltransferase
T76964	Valanafusp alfa
	Valanafusp alfa (AGT-181) is a recombinant fusion protein that combines a chimeric monoclonal antibody targeting the human insulin receptor (HIR) with human iduronidase (IDUA), facilitating brain penetration. It is utili...
TP1777	P2Ca
	p2Ca, a naturally processed peptide that derives from a ubiquitous enzyme, alpha-ketoglutarate dehydrogenase, and is recognized in association with the class I MHC protein, Ld, by a CTL clone (2C).
T39315	I-PEG5-OH	I-PEG5-OH
	I-PEG5-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within ...
T15670	KT5823		Apoptosis , PKA
	KT5823 is a selective and potent cGMP-dependent protein kinase (PKG) inhibitor with inhibitory effects on PKA and PKC.KT5823 increases thyroid-stimulating hormone-induced (Na+/I- symporter) NIS expression and iodide ion ...		Apoptosis , PKA
T38772	I-PEG6-OH	I-PEG6-OH
	I-PEG6-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within ...
T23506	Viomycin		Others
	Viomycin is a member of the tuberactinomycin family of antibiotics. Viomycin also inhibits group I intron splicing and prokaryotic protein synthesis. Freezes bacterial ribosomes in either the pre- or post-translational s...		Others
T61080	L-I-OddU
	L-I-OddU, a potent and selective anti-Epstein-Barr virus (EBV) agent, is a L-5'-halo-dioxolane nucleoside analogue. It demonstrates antiviral activity by effectively suppressing replicative EBV DNA and viral protein synt...
T36678	Rp-8-CPT-cAMPS sodium
	Rp-8-CPT-cAMP is a structural combination of the lipophilic and non-hydrolyzable cAMP analogs, 8-CPT-cyclic AMP and Rp-cyclic AMPS .[1] It functions as a site-selective inhibitor of protein kinase A (PKA) type I and II, ...
T71930	APKC-I
	aPKC-I is an inhibitor of atypical protein kinase C (aPKC ) which inhibits both PKCζ and PKCι with high specificity and prevents VEGF-induced endothelial permeability in cell culture and in vivo, thereby blocking ischemi...
T69908	Pidnarulex HCl
	Pidnarulex HCl is the salt form of CX-5461, a first-in-class non-genotoxic small molecule targeted inhibitor of RNA polymerase I (Pol I) that activates the p53 pathway without causing DNA damage. CX-5461 selectively inhi...
T75992	Buforin II
	Buforin II, a powerful antimicrobial peptide originating from Buforin I (a protein extracted from the Asian toad Bufo bufo gargarizans's stomach), exhibits broad-spectrum antimicrobial properties against both Gram-positi...
T38807	[Lys8, Lys9]-Neurotensin (8-13)	JMV438,[Lys8, Lys9]-Neurotensin (8-13)
	[Lys8, Lys9]-Neurotensin (8-13) (JMV438) is a Neurotensin analog that elicits analgesic effects by activating the G protein-coupled receptors NTS1 and NTS2. The compound has K i values of 0.33 nM and 0.95 nM for hNTS1 an...
T11500	GSK3368715	EPZ019997	Histone Methyltransferase
	GSK3368715 is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50s: 3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRM...		Histone Methyltransferase
T83547	(Des-Bromo)-Neuropeptide B (1-23) (human)
	'(Des-Bromo)-Neuropeptide B (1-23) (human)' is an agonist for orphan G-protein-coupled receptors, exhibiting a K i of 1.2 nM for GPR7 (NPBW1) and 341 nM for GPR8 (NPBW2) respectively [1].
T80059	Complement factor I		Endogenous Metabolite
	Complement factor I, a serine protease, attenuates complement activity both in the fluid phase and on cell surfaces, working alongside cofactors such as factor H (FH), complement receptor 1 (CR1/CD35), C4 binding protein...		Endogenous Metabolite
T76021	Myelin Basic Protein TFA
	Myelin Basic Protein (MHP4-14) TFA, a synthetic peptide containing residues 4-14 of myelin basic protein, serves as a highly selective substrate for protein kinase C (PKC) with a K_m of 7 μM. It is not phosphorylated by ...
T39311	Tyrosinase-related Protein 2 (TRP-2) (181-188)
	Tyrosinase-related Protein 2 (TRP-2) (181-188) is a peptide derived from the tyrosinase-related protein 2 (TRP-2), specifically corresponding to residues 180-188. It is the primary epitope within TRP-2 that is recognized...
T14945	CH-0793076	TP3076	Topoisomerase
	CH-0793076, a hexacyclic camptothecin analog, is an active drug and major metabolite of TP300. CH-0793076 is efficacious against cells expressing BCRP (breast cancer resistance protein). CH-0793076 inhibits DNA topoisome...		Topoisomerase

Compounds

KNK437

T2444

Synonym: Heat Shock Protein Inhibitor I

Target: Epigenetic Reader Domain

RSVA405

T8476

Synonym: RSVA 405

Target: AMPK, STAT, Autophagy

Bisindolylmaleimide I

T6513

Synonym: GF109203X,Go 6850

Target: PDGFR, PKC

Oxaprozin

T0708

Synonym: Oxaprozinum,Wy21743

Target: Epigenetic Reader Domain, Histone Acetyltransferase

Synonym: Isepamicine (Isepamycin,Isepamicin Sulphate,Isepacin,sch21420) Sulphate

Target: Antibacterial, Antibiotic

Pyridaben

T5114

Synonym:

Target: Calcium Channel, Parasite

p2Ca acetate(142606-55-1 free base)

Synonym: Etrenol(mesylate),Win 249-33

Target: DNA/RNA Synthesis, Topoisomerase, Parasite

Copanlisib dihydrochloride

T14998

Synonym: BAY 80-6946 dihydrochloride

Target: Apoptosis, PI3K, mTOR

Tubulin inhibitor 35

T77584

Synonym: Tubulin IN 35

Target: Apoptosis, Microtubule Associated, Topoisomerase

Amonafide

T6336

Synonym: NSC308847,AS1413,Nafidimide,AS1413,Quinamed

Target: Topoisomerase

GSK3368715 dihydrochloride

T11500L

Synonym: EPZ019997 dihydrochloride,GSK3368715 2HCl,EPZ019997 2HCl

Target: Histone Methyltransferase

ZW4864 free base

T9642

Synonym:

Target: Wnt/beta-catenin

MS023 dihydrochloride

T61338

Synonym: MS023 2HCl

Target: Histone Methyltransferase

IHMT-PI3Kδ-372 S-isomer

T60196

Synonym:

Target: PI3K

2-Bromo-4'-hydroxyacetophenone

T7084

Synonym: SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide

Target: EGFR, IκB/IKK

R 59-022 hydrochloride

T72322

Synonym: DKGI-I hydrochloride,Diacylglycerol kinase inhibitor I hydrochloride,DKGI-I hydrochloride ; Diacylglycerol kinase inhibitor I hydrochloride

Target: 5-HT Receptor, PKC

Quarfloxin

T16703

Synonym: CX-3543

Target: DNA/RNA Synthesis

Synonym: Ac-Gly-lys-phe-lys-arg-pro-pro-leu-arg-arg-val-arg-NH2,Tni peptide (104-115)

Synonym: Adam I 123,Adam I123

Target:

5-HT7R antagonist 1 free base

T39870

Synonym: 5-HT7R antagonist 1 free base

Synonym: EPZ019997 3HCl,GSK3368715(EPZ019997)

Target: Histone Methyltransferase

Target: Apoptosis, PKA

Rp-8-CPT-cAMPS sodium

[Lys8, Lys9]-Neurotensin (8-13)

T38807

Synonym: JMV438,[Lys8, Lys9]-Neurotensin (8-13)

Target: Histone Methyltransferase

(Des-Bromo)-Neuropeptide B (1-23) (human)

Target: Endogenous Metabolite

Myelin Basic Protein TFA

Target: Topoisomerase

Cat No.	Product Name	Synonyms	Targets
T3895	Polyphyllin I		Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
	Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D ha...		Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
T2787	Picroside I	6'-Cinnamoylcatalpol	MMP , STAT
	Picroside I (6'-Cinnamoylcatalpol), a hepatoprotective agent, is reported to be antimicrobial and used against hepatitis B. It has antioxidant, and anti-inflammatory activities, it may be the valuable anti-invasive drug ...		MMP , STAT
T4839	Ac-Ala-OH	N-Acetylalanine,N-Acetyl-L-alanine	Others , Endogenous Metabolite
	Ac-Ala-OH (N-Acetyl-L-alanine) is a substrate for Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Myelin basic protein, GTP-binding nuclear protein Ran, Tropomyosin alpha 4 chain, HIV-1 Rev binding pro...		Others , Endogenous Metabolite
T1020	Doxorubicin hydrochloride	Adriamycin,Doxorubicin (Adriamycin) HCl,Hydroxydaunorubicin hydrochloride,NSC 123127	Apoptosis , Mitophagy , HBV , HIV Protease , Topoisomerase , Antibacterial , Antibiotic , AMPK , Autophagy
	Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM). Doxorubicin hydrochloride exhibits cytotoxicity and antitum...
TN2080	Pinoresinol	(+)-Pinoresinol	Apoptosis , NF-κB , CDK , p53
	Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative st...		Apoptosis , NF-κB , CDK , p53
T6S1418	Praeruptorin C		Antioxidant , Calcium Channel
	1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors ...		Antioxidant , Calcium Channel
T64812	Collagenase Type I	Collagenase I,Collagenase Type I (From microorganisms)	Others
	Collagenase Type I is a proteolytic enzyme that breaks down the peptide bonds in collagen, the main structural protein of connective tissue. Collagenase has been explored as a potential treatment option to break down her...		Others
T6S1369	Vitexin	Apigenin-8-C-glucoside	Antioxidant
	1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can eit...		Antioxidant
T5S0106	Peimisine	Ebeiensine	RAAS , AChR
	1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe...		RAAS , AChR
T3826	Polygalasaponin F		NF-κB , TLR , Akt , PI3K
	Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Po...		NF-κB , TLR , Akt , PI3K
TN1718	Gymnemic acid I	(+)-Gymnemic acid I,Gymnemic acid I, (+)-	Others
	Gymnemic acid I (Gymnemic acid I, (+)-) inhibits protein biosynthesis with antisweet principles.		Others
T16726	Rebeccamycin		Topoisomerase
	Rebeccamycin is an antitumor antibiotic+ inhibits DNA topoisomerase I. Rebeccamycin appears to exert its primary antineoplastic effect by poisoning topoisomerase I. It also has a negligible effect on protein kinase C and...		Topoisomerase
TN2769	2-Hydroxynaringenin		Others
	The recombinant protein exhibits high FNS I activity catalyzing the conversion of naringenin to apigenin and 2-Hydroxynaringenin.		Others
TN6458	Acetylshikonin
	Acetylshikonin can effectively inhibit tumor cells, it can be used to treat hepatocellular carcinoma cells expressing hepatitis B virus X protein (HBX) by inducing ER stress , an oncoprotein from hepatitis B virus. Acety...
T75540	Ipomoeassin F
	Ipomoeassin F, a selective and potent inhibitor of endoplasmic reticulum (ER) protein translocation, targets the Sec61 complex's pore-forming subunit (Sec61α) at the ER membrane. It inhibits the ER membrane translocation...
T15703	Lactimidomycin		Others
	Lactimidomycin, isolated from Streptomyces, is an inhibitor of eukaryotic translation elongation. It is also a potent and non-toxic inhibitor of dengue virus 2 and other RNA viruses. Lactimidomycin has an antiproliferati...		Others
T36295	Echistatin TFA
	Echistatin TFA, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorpti...

Natural Products

Polyphyllin I

T3895

Synonym:

Target: Apoptosis, Akt, JNK, PDK, mTOR, Autophagy

Picroside I

T2787

Synonym: 6'-Cinnamoylcatalpol

Target: MMP, STAT

Ac-Ala-OH

T4839

Synonym: N-Acetylalanine,N-Acetyl-L-alanine

Target: Others, Endogenous Metabolite

Doxorubicin hydrochloride

T1020

Synonym: Adriamycin,Doxorubicin (Adriamycin) HCl,Hydroxydaunorubicin hydrochloride,NSC 123127

Target: Apoptosis, Mitophagy, HBV, HIV Protease, Topoisomerase, Antibacterial, Antibiotic, AMPK, Autophagy

Pinoresinol

TN2080

Synonym: (+)-Pinoresinol

Target: Apoptosis, NF-κB, CDK, p53

Praeruptorin C

T6S1418

Synonym:

Target: Antioxidant, Calcium Channel

Collagenase Type I

T64812

Synonym: Collagenase I,Collagenase Type I (From microorganisms)

Target: Others

Vitexin

T6S1369

Synonym: Apigenin-8-C-glucoside

Target: NF-κB, TLR, Akt, PI3K

Gymnemic acid I

TN1718

Synonym: (+)-Gymnemic acid I,Gymnemic acid I, (+)-

Target: Topoisomerase

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-00252	Bovine coronavirus (strain Mebus) Protein I (His)	BCoV	E. coli
	Structural protein that is not essential for the viral replication either in tissue culture or in its natural host. Bovine coronavirus (strain Mebus) Protein I (His) is expressed in E. coli expression system with C-6xHis...
TMPH-00256	Bovine coronavirus (strain LY-138) Protein I (His)	BCoV	E. coli
	Structural protein that is not essential for the viral replication either in tissue culture or in its natural host. Bovine coronavirus (strain LY-138) Protein I (His) is expressed in E. coli expression system with C-6xHi...
TMPH-00254	Bovine coronavirus (strain 98TXSF-110-ENT) Protein I (His)	BCoV	E. coli
	Structural protein that is not essential for the viral replication either in tissue culture or in its natural host. Bovine coronavirus (strain 98TXSF-110-ENT) Protein I (His) is expressed in E. coli expression system wit...
TMPH-00253	Bovine coronavirus (strain 98TXSF-110-LUN) Protein I (His)	BCoV	E. coli
	Structural protein that is not essential for the viral replication either in tissue culture or in its natural host. Bovine coronavirus (strain 98TXSF-110-LUN) Protein I (His) is expressed in E. coli expression system wit...
TMPH-00255	Bovine coronavirus (strain LSU-94LSS-051) Protein I (His)	BCoV	E. coli
	Structural protein that is not essential for the viral replication either in tissue culture or in its natural host. Bovine coronavirus (strain LSU-94LSS-051) Protein I (His) is expressed in E. coli expression system with...
TMPY-00695	I-309 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	I-309 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35 kDa and the accession number is P22362.
TMPY-03855	DNase I Protein, Human, Recombinant (His)	Human	HEK293 Cells
	DNase1, also known as deoxyribonuclease I and DNL1, is a member of the DNase family. DNaseI is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phos...
TMPY-04878	IGF1/IGF-I Protein, Mouse, Recombinant	Mouse	P. pastoris (Yeast)
	IGF1/IGF-I Protein, Mouse, Recombinant is expressed in yeast. The predicted molecular weight is 7.7 kDa and the accession number is E9PU89.
TMPY-06982	IGF1/IGF-I Protein, Human, Recombinant	Human	E. coli
	IGF1/IGF-I Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.8 KDa. and the accession number is P05019-1.
TMPY-02899	Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.2 kDa and the accession number is Q00623.
TMPY-04415	CAMKI Protein, Human, Recombinant	Human	E. coli
	CAMKI Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 41.5 kDa and the accession number is B0YIY3.
TMPJ-01053	UBE2I Protein, Human, Recombinant (GST)	Human	E. coli
	SUMO-Conjugating Enzyme UBC9 (UBC9) belongs to the ubiquitin-conjugating enzyme family. UBC9 is homologous to ubiquitin-conjugating enzymes (E2s). However, instead of conjugating ubiquitin, UBC9 conjugates a ubiquitin ho...
TMPJ-00814	RBP1 Protein, Human, Recombinant	Human	E. coli
	RBP1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14 KDa and the accession number is P09455.
TMPY-02249	FABP6 Protein, Human, Recombinant	Human	E. coli
	Gastrotropin, also known as Fatty acid-binding protein 6, Ileal lipid-binding protein, ILBP, Intestinal 15 kDa protein, Intestinal bile acid-binding protein, I-BABP and FABP6, is a cytoplasm protein which belongs to t...
TMPY-00320	APOA1BP Protein, Human, Recombinant (His)	Human	HEK293 Cells
	APOA1BP, now renamed NAXE, encodes an epimerase essential in the cellular metabolite repair for NADHX and NADPHX. The enzyme catalyzes the epimerization of NAD(P)HX, thereby avoiding the accumulation of toxic metabolites...
TMPH-01092	CHGA Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	CHGA Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 50.9 kDa and the accession number is P10645.
TMPJ-00529	FABP6 Protein, Human, Recombinant (His)	Human	E. coli
	Fatty Acid-Binding Protein 6 (FABP6) is cytoplasmic protein that binds long-chain fatty acids and other hydrophobic ligands which belongs to the calycin superfamily. FABP6 expression is restricted in the small intestine ...
TMPY-02051	FABP2 Protein, Human, Recombinant (His)	Human	E. coli
	Fatty acid binding protein (FABP) is one of the intracellular proteins, with a low molecular weight of approximately 15 kDa, that plays important roles in the transportation and metabolism of long-chain fatty acids. FABP...
TMPJ-00528	PPP1R1A Protein, Human, Recombinant (His)	Human	E. coli
	Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen metabolism, IPP-1 protein pla...
TMPJ-00702	APT-1 Protein, Human, Recombinant (His)	Human	E. coli
	Acyl-Protein Thioesterase 1 (APT-1) is lysophospholipase that belongs to the AB hydrolase 2 family. Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. APT-1...
TMPJ-00766	ANXA1 Protein, Human, Recombinant	Human	E. coli
	Annexin A1 is the first characterized member of the annexin family of proteins and is able to bind to cellular membranes in a calcium-dependent manner, promoting membrane fusion and endocytosis. Annexin A1 has anti-infla...
TMPY-03864	CRABP1 Protein, Human, Recombinant	Human	E. coli
	CRABP1 is a specific binding protein for a vitamin A family member. It is thought that CRABP1 plays an important role in retinoic acid-mediated differentiation and proliferation processes. CRABP1 is structurally similar ...
TMPY-05207	PRKAR1A Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	PRKAR1A Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 44.6 kDa and the accession number is Q9DBC7.
TMPJ-01112	PRKG1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	cGMP-Dependent Protein Kinase 1 (PRKG1) belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. PRKG1 contains one AGC-kinase C-terminal domain, two cyclic nucleotide-binding domains, and one pro...
TMPJ-00240	CAMK1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Calcium/Calmodulin-Dependent Protein Kinase Type 1 (CAMK1) belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, and CaMK subfamily. CAMK1 contains one protein kinase domain and widely expressed....
TMPY-01769	4EBP1 Protein, Human, Recombinant (His)	Human	E. coli
	The translational suppressor eIF4E binding protein-1, 4E-BP1 functions as a key regulator in cellular growth, differentiation, apoptosis and survival. The Eif4ebp1 gene, encoding 4E-BP1, is a direct target of a transcrip...
TMPH-01212	DNASE1L3 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA...
TMPH-01213	DNASE1L3 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA...
TMPH-01214	DNASE1L3 Protein, Human, Recombinant	Human	E. coli
	Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA...
TMPJ-00799	ANXA2 Protein, Human, Recombinant	Human	E. coli
	Annexin A2 (ANXA2) is a member of the annexin family and has roles in the regulation of cellular growth and in signal transduction pathways. ANXA2 protein is associated with sickle cell osteonecrosis and the expression r...
TMPK-01239	THSD7A Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Thrombospondin type I domain-containing 7A (THSD7A), is a specific autoantigen of adult idiopathic membranous nephropathy (IMN), whose circulating antibody (THSD7A-AB) represents a promising biomarker for diagnosis of IM...
TMPJ-00923	Calnexin Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Calnexin/CANX is a single-pass type I membrane protein which belongs to the calreticulin family. It consists of a large N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), a...
TMPY-03071	I-309 Protein, Human, Recombinant	Human	E. coli
	I-309 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.7 kDa and the accession number is P22362.
TMPY-00499	TMP21 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	TMED10 disrupts the complex formation between TGF-beta type I (also termed ALK5) and type II receptors (TbetaRII). Misexpression studies revealed that TMED10 attenuated TGF-beta-mediated signaling. A 20-amino acid-long r...
TMPH-03209	CLNS1A Protein, Rabbit, Recombinant (His & Myc)	Rabbit	E. coli
	CLNS1A Protein, Rabbit, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.4 kDa and the accession number is Q28678.
TMPY-06726	Car i 1 Protein, Pecan, Recombinant	Pecan	E. coli
	Car i 1 Protein, Pecan, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.7 kDa.
TMPY-02538	I-309 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	I-309 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36.2 kDa and the accession number is P10146-1.
TMPH-00941	RIG-I Protein, Human, Recombinant (His)	Human	E. coli
	RIG-I Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 53.3 kDa and the accession number is O95786.
TMPJ-00304	ALK-1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-β superfamily of ligands, which mediates signaling of BMP9 (bone morphogenetic protein) and BMP10. ALK1 signaling is necessary for angi...
TMPJ-00482	SEMG1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Semenogelin-1 (SEMG1) is the predominant protein in semen; it is a secretory protein involved in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. The prostate-specific a...
TMPJ-00021	LGALS1 Protein, Human, Recombinant (His)	Human	E. coli
	Galectin-1 is a member of growing family of evolutionary conserved animal lectins. Galectin-1 is widely expressed in many cells and tissues. Galectins consists of a Galectin domain and two Beta-galactoside binding domain...
TMPY-03656	PRKAR1A Protein, Human, Recombinant (His)	Human	HEK293 Cells
	PRKAR1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.2 kDa and the accession number is P10644.
TMPH-00905	ADIPOR1 Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	ADIPOR1 Protein, Human, Recombinant (His & Myc & SUMO) is expressed in in vitro E. coli expression system.
TMPY-06690	Ses i 1 Protein, Sesamum indicum, Recombinant	Sesamum indicum	E. coli
	Ses i 1 Protein, Sesamum indicum, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 29.2 kDa.
TMPH-00074	GlcNAcT-I Protein, Arabidopsis thaliana, Recombinant (His)	Arabidopsis thaliana	Baculovirus Insect Cells
	Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. Required for normal root growth and morphology. GlcNAcT-I Protein, Arabidopsis thaliana, R...
TMPY-06672	Car i 1 Protein, Carya illinoinensis, Recombinant	Carya illinoinensis	E. coli
	Car i 1 Protein, Carya illinoinensis, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 59.5 kDa.
TMPH-00273	IGF1/IGF-I Protein, Bovine, Recombinant (hFc)	Bovine	P. pastoris (Yeast)
	IGF1/IGF-I Protein, Bovine, Recombinant (hFc) is expressed in yeast with N-hFc tag. The predicted molecular weight is 34.3 kDa and the accession number is P07455.
TMPH-03314	IGF1/IGF-I Protein, Rat, Recombinant (GST)	Rat	E. coli
	N/A. IGF1/IGF-I Protein, Rat, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 34.7 kDa and the accession number is P08025.
TMPK-00776	Complement factor I Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I P...
TMPJ-00158	Apolipoprotein A-I/APOA1 Protein, Human, Recombinant	Human	E. coli
	Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various...
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